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Autoimmune Bullous Diseases and Quality of Life
Bookmark1. Skin-related quality of life is associated with the type of autoimmune bullous disease and flare state. 2. Skin-related quality of life can inform changes in disease state and severity of...
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3-dimensional stereophotogrammetry for craniofacial morphea disease progression
Bookmark1. 3-dimensional (3D) stereophotogrammetry identified craniofacial morphea (CM) progression in patients with clinically reported disease activity. 2. 3D stereophotogrammetry identified the...
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Spesolimab may improve quality of life in patients with generalized pustular...
1. Efficacy of spesolimab appeared to be dose-dependent with high-dose spesolimab leading to a significantly longer time to GPP flare-up versus placebo. 2. There were no treatment-related deaths or...
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Current expert consensus for the treatment of adult patients with drug...
1. A large majority of experts in this study came to a unified consensus on how to approach the diagnosis and treatment of patients with drug reaction with eosinophilia and systemic symptoms (DRESS)....
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IL-23 inhibitors may have a lower risk of paradoxical eczema in comparison to...
1. Interleukin-23 inhibitors had a lower risk of developing paradoxical eczema when treated for plaque psoriasis compared to TNF inhibitors, IL-17 inhibitors and IL-12/23 2. Clinical features...
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First-line rituximab for pemphigus associated with long-term complete...
1. Patients with pemphigus treated with first-line rituximab showed sustained complete remission rates without corticosteroids for up to 7 years post-treatment 2. High-risk patients for pemphigus...
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Interleukin-23 receptor antagonist improves psoriasis symptoms
1. In this randomized controlled trial, treatment with JNJ-77242113 improved psoriasis symptoms as compared to a placebo. 2. JNJ-77242113 showed a dose-response relationship, with higher doses...
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Radiation treatment for breast cancer may increase incidence of...
1. Amongst a cohort of breast cancer survivors, those that were treated with radiation had a higher risk of developing nonkeratinocyte skin cancer. Evidence Rating Level: 2 (Good) Cancer remains the...
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Individualized cancer mRNA-based cancer therapy shows benefit in patients...
1. 18-month recurrence-free survival was significantly greater in the combination therapy group compared to pembrolizumab alone. 2. There were no treatment-related grade 4-5 adverse events or...
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Intravenous ertapenem for hidradenitis suppurativa
1. Intravenous ertapenem administered for a mean of 13 weeks for patients with hidradenitis suppurativa was associated with improvement in clinical outcomes, inflammatory markers, and patient...
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